DMSO Dimethyl Sulfoxide Research for Cancer Treatment

Every cancer patient’s nightmare is the high toxicity of chemotherapy, with its horrible side effects. Chemotherapy kills cancer cells; it can also kill the patient. Is this something that cannot be helped? Is it inevitable?

If you ask your MD or oncologist, they will tell you with a sad smile that unfortunately, for the present moment, it is beyond the power of medical science to make chemotherapy selectively target cancer cells.

Nothing could be further from the truth!

There are two legal, safe, effective and inexpensive methods to make chemotherapy selective to cancer cells. One is IPT, described in another report on this website. The other one is DMSO potentiation. Both methods are completely ignored and stubbornly resisted by the medical establishment, despite irrefutable and overwhelming proof of efficacy and safety. In other words, when your oncologist prepares a chemotherapeutic course for you, it will be highly toxic and damaging to your body, despite the fact that methods exist – and are being legally practiced by medical doctors – that reduce the toxicity of chemotherapy virtually to zero.

What is DMSO?

Short for Dimethyl Sulfoxide, DMSO is a 100% natural substance; a byproduct of the lumber industry, which supplies it to the pharmaceutical industry for veterinary and human use. Already 40 years ago, it was discovered that dimethyl sulfoxide (DMSO) had a very high affinity for cancer cells. In other words, DMSO targeted cancer cells.

DMSO could bind to other substances, and still target cancer cells. It is one of the most powerful carrier/solvent known to science. It is able to bind to certain types of molecules, and then carry these molecules inside cancer cells.

The original scientific study which first proved this is the following:
“Haematoxylon [a dye] Dissolved in Dimethylsulfoxide [DMSO] Used in Recurrent Neoplasms [i.e. cancer cells or tumor cells],” by E. J. Tucker, M.D., F.A.C.S., and A. Carrizo, M.D. in International Surgery, June 1968, Vol 49, No. 6, page 516.


The study had been carried out by Eli J. Tucker, M.D. and A. Carnizo, M.D. In the study it was shown that DMSO targeted cancer cells, as the DMSO carried the haematoxylon dye into the cancer cells. It has also been shown that DMSO is able to revert cancer cells into normal cells. The study involved 37 human pre-terminal patients. The results of the study were declared “insufficient evidence” by the hospital’s review committee, and the study has been completely ignored by the mainstream medical establishment.

From the study:

In this series of 37 preterminal cases of malignancy that were treated with dimethylsulfoxide and Haematoxylon therapy, there was an improvement in 70.5 percent of the cases when used with combined current cancer therapeutic agents. These agents included surgery, radiation, 5-fluonouracil, methotnexate and thio-tepa. There was improvement in only 5.4 percent of those cases treated with the above measures without the use of dimethylsulfoxide and Haematoxylon.

The most striking results were observed in the two cases of large-cell lymphosarcoma and two cases of malignant giant-cell tumor of the bone. There was complete regression in both of the cases of large-cell lymphosancoma with no recurrence to date. There was also complete regression in one case of malignant giant-cell tumor of the femur with no recurrence to date and one case of a highly malignant giant-cell tumor of approximately one third of the femur which is still in a state of regression with bone regeneration.

With DMSO the improvement was 70.5 percent, without DMSO it was 5.4 percent. This has been the first human trial, using experimental procedure without any previous experience, and without the highly refined DMSO that has since been developed for medical use.

Since then, countless research studies have been carried out in many countries by medical research scientists. More than 40,000 articles have been published on the chemistry of DMSO in conjunction with thousands of laboratory studies, and world wide, there are over 11,000 articles on DMSO’s medical and clinical implications from some 125 countries. On the internet, in PubMed, the word, DMSO, brings up 15,478 research articles, the term, DMSO cancer, brings up 2,539 research articles.

Dr. Stanley Jacob MD, the ” Father of DMSO”, researched DMSO for decades, and written several books about it. Dr. William C. Douglass, MD – voted “Doctor of the Year” by the National Health Federation – personally saw so much promise with DMSO, he gave a three-day medical conference comprised of DMSO experts from around the world.

Writes Dr. Ron Kennedy, M.D., at

When you consider the fact that DMSO is not a new and patentable drug, is cheap, safe and effective, and knowing what you should know about the medical establishment in the U.S., you could predict with your eyes closed that there is a propaganda campaign against DMSO. The FDA has done nothing except drag its feet in DMSO research since October 25, 1963 when the first research application to study DMSO was filed with that agency.


The FDA decided that DMSO was a dangerous drug and notified all the drug companies involved in DMSO research (Squibb, Syntex, Merck) to halt all clinical trials. Then they issued press releases that DMSO caused cataracts even though DMSO had never caused cataracts in any study, animal or human. On the contrary, research has shown that DMSO improves vision and is an effective treatment for retinitis pigmentosa and macular degeneration. The FDA used the bogus issue of eye damage for several decades to hold back DMSO. DMSO is seven times safer than aspirin yet has been persecuted for decades by the FDA.
See book: The Persecuted Drug – The Story of DMSO by Pat McGrady Sr.
(available at Amazon).

DMSO was first reported in 1963 by Stanley Jacob, M.D. of the University of Oregon Medical School, former head of the organ transplant program at Oregon Health Sciences University in Portland. Jacob claimed that DMSO could penetrate skin and produce local analgesia, decrease pain, and promote healing of injured tissue. According to Jacob, more than 40,000 articles on its chemistry have appeared in scientific journals, which, in conjunction with thousands of laboratory studies, provide strong evidence of a wide variety of remarkable properties.

DMSO is one of the most studied but least understood pharmaceutical agents of our time – at least in the United States. Doctors around the world prescribe DMSO for a variety of ailments, including pain, inflammation, scleroderma, interstitial cystitis, and arthritis elevated inter-cranial pressure. Millions of patients were treated with it, without a single reported case of fatality, or serious injury, yet it continues to be ignored decade after decade by conventional medicine.

DMSO binds with water and changes the structure of the water within the cell, which results in the healing of cellular damage. This also increases the permeability of the cell membrane, causing a flushing of toxins from the inside of the cell. DMSO also improves immune function, decreases allergic reactions, increases immunity to infections, prohibits cancer growth, and decreases the potency of toxins. DMSO crosses the blood-brain barrier, and is an excellent agent to help transport other substances throughout the body.

When used for pain relief, chronic pain patients often report relief to a degree they had not been able to obtain from any other source. The anti-inflammatory and pain relief properties of DMSO have made it the most widely used, approved treatment for interstitial cystitis (irritation of the urinary tract) in the world.  The treatment is FDA approved.

DMSO also reduces inflammation by several mechanisms. It is an antioxidant – a scavenger of the free radicals that gather at the site of injury. DMSO also stabilizes membranes and slows or stops leakage from injured cells.

Stephen Edelson, MD, F.A.A.F.P., F.A.A.E.M., who practices medicine at the Environmental and Preventive Health Center of Atlanta, has used DMSO extensively for 4 years. “We use it intravenously as well as locally”, he says. “We use it for all sorts of inflammatory conditions, from people with rheumatoid arthritis to people with chronic low back inflammatory-type symptoms, silicon immune toxicity syndromes and any kind of autoimmune process.”
What is the significance of DMSO in the fight against cancer? What does this substance mean to the cancer patient?

It means that a number of safe and effective cancer treatments can be designed that otherwise would not even exist.

DMSO is a superb, non-toxic solvent/carrier. Writes Dr. Morton Walker, MD, in his book, DMSO – NATURE’S HEALER (Amazon):

” As a penetrating carrier of drugs, DMSO is unsurpassed. It easily carries necessary pharmaceuticals to any part of the body for a therapeutic effect. It passes through cellular membranes and tissues. It is invariably able to penetrate endothelial coatings of the arterial walls, meninges of the brain, healthy skin, mucous membranes, and other tissues. ”

This enables DMSO to turn highly toxic treatments into benign, non-toxic ones. It also enables it to potentiate substances, elevating them to the level of powerful and safe anti-cancer agents. Let us take a look at these, one by one.

Please note: The below description of possible uses of DMSO are given as educational and experimental information, not as medical advice. Always discuss your therapeutic plans with a licensed health care practitioner. The following information has been obtained from public domain sources, as well as through interviews with research scientists and licensed medical practitioners.

Having said that, I’ll also add this: In my opinion, DMSO potentiation brings a revolution into medicine, because the individual who is seeking a solution better than the one offered by his or her oncologist, is free to try out non-toxic, non-prescription and non-invasive methods, without spending a fortune. This brings us, as patients, a step closer to medical freedom.

DMSO – intravenously, all by itself
DMSO – topically, all by itself
DMSO – orally, all by itself
DMSO — IPT (intravenous)
DMSO — chemotherapy (intravenous)
DMSO — nano-silver (topical/oral)
DMSO — cesium chloride (topical/oral)
DMSO — zeolite (topical/oral)
DMSO — ellagic acid (topical/oral)
DMSO — squalene/squalamine (oral)
DMSO — sodium bicarbonate (intravenous)

In the following treatment modalities, DMSO is regarded both as a carrier and as a healing substance. The fact that DMSO is inexpensive and safe makes it possible and realistic for the cancer patient to experiment with different protocols. Some may claim that these protocols are bizarre. Personally, I cannot imagine any treatment more bizarre than the one that introduces deadly poisons into the body, and has been proven obsolete, barbaric and ineffective through almost a century-long use.

DMSO – intravenously, all by itself
DMSO is a potent anti-cancer agent all by itself. At the present moment, there is only one clinic in the United States that offers “stand alone” intravenous DMSO treatments to cancer patients, administered and supervised by experienced medical doctors. Although they use various treatment modalities, their central cancer therapy is based on intravenous DMSO, where DMSO is not used as a carrier or potentiator, but as the main drug of the treatment. Click here for further details on the clinic.

DMSO – topically, all by itself
According to Dr. Walker, M.D., DMSO as a penetrating substance is unsurpassed. “It passes through cellular membranes and tissues. It is invariably able to penetrate endothelial coatings of the arterial walls, meninges of the brain, healthy skin, mucous membranes, and other tissues.” What does this tell us? It suggests that when injections or intravenous infusion are not available, DMSO, as an anti-cancer agent, can be introduced into the body safely and effectively through the skin. This is being done for sport injuries, arthritis, shingles, etc. by millions of people since more than 30 years. Here is how someone who has developed and patented a special DMSO formula for health purposes, including his and his family’s aches and pains, describes its topical use:

(The product these instructions refer to is a liquid solution called DMSO.BZ. It is an odorless clear liquid, similar to water. Please note that the developer of this formula does not claim that the product is a cancer treatment.)

Apply the solution with a cotton ball, pad, or even the fingers, to the area to be treated.  Put on an ample coating, but not enough that it drips off, and cover the areas surrounding the injured area also, for a couple of inches.  If you wish more rapid absorption, you can softly rub the area.  If you choose to do this, don’t rub too much, or too hard, as you can irritate the skin.  If you use your fingers, which I do a lot, you don’t even have to wash it off – just rub it into your hands.  It helps them and aids the tissues and joints, so why waste it?

Don’t contaminate the bottle.  Always pour some solution into a small glass, cup, or other container, and apply from this container.  You don’t have to throw out the cotton ball, or pad after each application- just drop it in the glass with the solution you poured out, until you are going to apply it again later.  If you want to be extra safe, cover the container with some plastic wrap between applications.  I don’t bother with this, but it is not a bad idea, as the DMSO can absorb things from the air.

Within a few minutes you will notice the solution being absorbed into the skin.  If you do notice some stinging (this may be accompanied by some redness), especially in very tender areas, such as the neck and face, it usually goes away in just a few minutes.

The sooner you apply the solution to the injured area, after injury, the quicker the healing process can begin, and some of the pain and tissue damage can actually be curtailed, and much of the bruising eliminated.

After the initial application, an additional application can be made after one half hour to one hour.  You can continue applying the solution thereafter, every hour, or several hours, until the desired relief is obtained.  This is quite an individual thing, and varies from injury to injury and from area to area, and, sometimes, even person to person.  You can, and will, experiment on yourself and you will shortly determine what works for you.  If you have chronic arthritis, or other pain, you may end up using an application, or two, every day to ease the pain, or keep the pain away entirely.

It would be hard to use too much  of my DMSO solution, as it is classified as one of the safest products known.  DMSO is naturally present in many of our food products and it has even been conjectured that it most likely exists naturally in human tissue.  It is also stated that its derivative, MSM is definitely found at the cellular level (see the literature).  If you use it too often on any given area, or rub too hard, about the only problem you will incur is a little burning and redness.  After several days, though this is rare, except in the most tender areas, you may also notice some of the surface skin peeling, or flaking off, just like in mild sunburn. 

If you do put it on too often, rub too hard, or use it on a very tender, thin skinned area, and get the burning sensation and redness, you may also notice some itching – yes, just like in a  case of mild sunburn.  If this occurs you can use some pure, high quality, skin cream, or plain old honey.  If you use skin cream, just make sure it does not have many chemical additives, as they will also be absorbed into the skin, if you are continuing to apply the dmso solution. 

At the bottom of this page you will find further information on this product. (Please note: I do not receive any commission or payment from any of the manufacturers, distributors, doctors and clinics listed on this website.)
The distributor is also available for consultation – free of charge – with his customers, but please, do not try to discuss cancer treatments with him, as he is not licenced to give medical advice. However, he can give you practical advice on how to handle the product.

You have seen earlier that there is a clinic in the USA where cancer is being treated by intravenous DMSO. Now we are looking at a treatment that uses DMSO through the skin to fight cancer. In order to bring enough DMSO into the body to make a difference, the solution can be applied repeatedly, in every two-three hours if needed. It can also be applied to relatively large areas on the body. Remember that DMSO actively and selectively seeks out cancer cells. This has been proven beyond doubt in animal and human studies. The biochemical reasons are not well understood, but the fact remains that DMSO targets cancer cells. It is also able to reach brain tumors because it is capable of passing through the blood/brain barrier. This has also been proven. According to the clinic where DMSO is infused intravenously to cancer patients, the treatment is used very successfully for aggressive brain tumors.

Should DMSO be used alone, by itself, or should it be combined with another anticancer agent? This has to be decided by the patient him/herself. An experienced naturopath or holistic doctor should be consulted before embarking on a treatment course. The potential combinations, listed below, may help in the decision. These therapies are by no means the only ones that can be tried. For example, at the clinic mentioned above, laetril is being occasionally used together with DMSO. There are many other variations that could be explored. Here, I only mention anti-cancer substances that are supported by sufficient scientific and clinical evidence, and where we are certain that they can be used with DMSO.

Not every anti-cancer remedy or substance can be combined with DMSO. Some will neutralize its effects, others will cause complications. For example, it is not clear whether it can be used in conjunction with Cantron or Protocel. It is better not to try.

To be absolutely certain that DMSO will not cause nausea, it is better not to use it with an empty stomach. This doesn’t mean that one should eat before each application, but the stomach should not be entirely empty.

DMSO – orally, all by itself
The premise is the same as with topical application, with one difference. The topical application is not likely to cause serious side effects; the oral ingestion has limits, set by how much DMSO is accepted by the stomach. People with a sensitive stomach may find that more than 2-3 tablespoonful will result in nausea or cramps. For maximum and fastest results, DMSO may be taken in small quantity (2 tablespoon a day) over and above the topical application. Never take it on an empty stomach. Eat a good breakfast or a snack before. If there is an allergic reaction to DMSO (not likely, but not impossible), stop using it, and choose another therapeutic approach.

Please note: DMSO in therapeutic quantites has zero toxicity. Should anyone drink several quarts of it, it may cause severe injury, even death. Although it is said to be seven times less toxic than aspirin, at the megadose level it is dangerous. Do not leave it out where children can reach it.

DMSO combined with IPT
In Insulin Potentiation Therapy the chemotherapeutic agents are carried into the glucose-starved cancer cells, thus selectively targeting them. Adding DMSO to the intravenous procedure enhances the targeting. Most doctors who offer IPT feel that this is not necessary, it would only duplicate the insulin’s results. This argument seems to ignore the well-known fact that DMSO has a powerful healing effect on abnormal cells all by itself. If the clinic offers both IPT and DMSO, combining the two can be discussed with the doctor.

DMSO Potentiated Chemotherapy
In this treatment, DMSO is used as a carrier to drag chemotherapeutic substances into cancer cells. Like in IPT, the objective is the selective targeting of cancer cells, using DMSO intravenously, together with the chemotherapy. Here, DMSO replaces the insulin as a targeting agent, although the biochemical procedure is not the same. In IPT, the insulin creates a condition where the chemo can be carried into the cells with the glucose solution. With DMSO, it is different. DMSO selectively seeks out cancer cells, acting like a “trojan horse” for the chemo.

DMSO Potentiated Nano-silver
This is a topical treatment, not intravenous.
Nano-silver is a new, powerful anti-microbial silver solution, where the size of the silver particles is a few nano-meters. At this size, the particles are a thousand times smaller than the colloidal particles in colloidal silver solutions, and they behave quite differently in the organism. For more on nano-silver, see the report.
From the report: Nano-silver doesn’t directly kill cancer cells; it kills bacteria, viruses and fungi. Cancer cells survive by fermenting glucose. Where there is fermentation, there is yeast. This means that there is a microbial presence within each cancer cell. If the fermenting bacteria die, the cancer cell either changes its metabolism to a normal one, or it also dies. In both cases, mission has been accomplished.

Nano-silver is small enough to penetrate a cancer cell. Once inside, it is believed that it will kill any microbial or viral presence. For this to happen, the nano-particles must be guided into the cancer cells. This is where DMSO comes into the picture. It selectively targets cancer cells, and it will “drag” the nano-silver into those cells. In this treatment, both the DMSO and the nano-silver solutions are applied topically (on the surface of the skin).

The treatment is completely non-toxic. Nevertheless, when applying DMSO to the skin, certain rules must be followed. Do not wear latex or rubber gloves, because DMSO will carry molecules from the material into your blood stream. Do not permit alcohol, soap, etc. to come in contact with the DMSO. If you use topically liquid DMSO, you can mix it with equal amount of nano-silver solution, and apply it to the skin. Do not rub it. Let it dry, then after 10 minutes, wipe it off gently.

The complete success of this treatment depends on the nano-silver’s ability of killing the microbe in the cancer cell. It has not yet been proven that nano-silver can kill all possible kinds of cancer microbes. Some cancers harbour viruses, some fungi, others bacteria. It is possible that all these microbial forms are the different pleomorphic stages of the same original microbe. If the microbe in the cancer cell is able to resist silver, the cancer cell will not be harmed by the silver. It has been demonstrated with colloidal silver that there are bacteria that do not respond to it, although they are rare. The good news is, even in such case, the DMSO, all by itself, will weaken or eliminate a large percent of the cancer cells it penetrates.

I have mentioned this possibility, not because I think that microbial resistance to nano-silver is likely, but because it has not yet been proven beyond doubt that such resistance is impossible, although the results from large number of tests so far are very positive. (See the nano-silver report.)

At the bottom of this page you will find sources where medical grade DMSO can be purchased.

The DMSO/nano-silver protocol can be done at home, without prescription or supervision; it is safe, simple, and inexpensive. Although the treatment can be repeated any number of times, it is advisable to apply the DMSO to the skin at different locations to avoid skin irritation.

Does nano-silver cross the blood/brain barrier? Can it be used to treat brain tumors? According the literature, nano-particles are able to pass through the BBB, however, so far no data is available based on controlled clinical trials.


“At the nano-scale, cellular uptake mechanisms are different, as particles below 20 nm can be taken up by the endothelium skin layers and those below 10-50 nm can enter cells through receptor mechanisms. Nanoparticles have been found to cross the blood-brain barrier.

From, FRI BRIEFINGS: Nanotechnology: A Brief Literature Review:

“Nanoparticles are readily taken up by many types of cells in vitro and are expected to cross the blood-brain barrier that excludes many substances that might harm the brain.

As nano-silver is safe, inexpensive, and commercially available, brain cancer patients may want to add it to their protocol, even without irrefutable evidence concerning the blood/brain barrier.

DMSO Potentiated Cesium chloride (topical/oral)
The following information is posted on about the Cesium chloride/DMSO treatment:

When it comes to treating advanced cancers, such as Stage IV cancers, fast growing cancers, cancers that have spread significantly, high fatality cancers, etc., if there were only one cancer treatment allowed to be used, this treatment would be the best choice. One reason for this is that it is the only “Stage IV” treatment that can be used at home for those who cannot take supplements or digest supplements.

While the Cesium Chloride / DMSO Protocol is extremely safe, given how powerful it is, before going on a Cesium Chloride Protocol, which must include DMSO, you need to DO YOUR HOMEWORK!!

Yes, indeed, you do have to do your homework. The way to do that is to have phone consultations with the vendor, or doctor who can guide you in the Cesium protocol. These can be found in the Cesium report.

This is an immensely powerful cancer treatment, but the rules are strict, and they must be respected. The manner in which DMSO is used in this therapy will be explained by the consultant or guide who has experience with this method. The treatment itself is described in the Cesium report.

DMSO Potentiated Zeolite
Zeolite is available both in powdered and liquid forms. As a liquid, it can be mixed with DMSO, and used both topically and orally. According to the literature, zeolite easily crosses the blood/brain barrier. This means that DMSO is able to carry it into brain tumors. Zeolite is not a drug, no prescription is needed, and it is entirely non-toxic. For more info on zeolite, see the report.

DMSO Potentiated Ellagic acid
Ellagic acid is available in capsule and powder forms. For more information on Ellagic acid, see the report. Ellagic acid, whether taken as food, or as a supplement, is totally harmless. There is no toxic dose, and no side effects. At the same time, it is a powerful anti-cancer substance. In other words, it kills cancer cells. In its powdered form it can be mixed with DMSO, and taken orally, or applied topically.

DMSO Potentiated Squalamine
“Our results suggest that squalamine may be well suited for humans in the treatment of brain tumors and other diseases characterized by and dependent on new blood vessel growth,” says Henry Brem, director of neurosurgical oncology at Hopkins.

Squalamine is an immune molecule; it is a powerful angiogenesis inhibitor, originally isolated from the liver of dogfish sharks. Squalamine becomes vitally important when there is a fast growing tumor, blocking blood circulation or pressing on a vital organ. By stopping tumor growth, Squalamine permits a slow, gradual elimination of the tumor or tumors to take place. When a tumor is being destroyed, the immune system reacts by inflammation and swelling. This, in case of a brain tumor, can become a serious concern. Trials with laboratory animals indicate that Squalamine is capable of passing the blood/brain barrier.

As a supplement, squalamine is available in capsule form. Through a naturopathic doctor, it may be available in liquid form and of pharmaceutical grade. Squalamine capsules can be taken orally, followed immediately by DMSO, also taken orally. Do not take these substances on an emptry stomach.

Squalamine, as well as DMSO, is safe and non-toxic. No prescription is needed.

DMSO — sodium bicarbonate

This protocol combines Dr. Tullio Simoncini’s sodium bicarbonate treatment concept with DMSO, at the suggestion of the author of this website. The preliminary results are so impressive that the protocol promises to become the most effective cancer treatment in existence. The combination is only available at the Camelot Cancer Care clinic in Tulsa, Oklahoma, but any medical doctor or naturopath with a licence to give intravenous treatments can apply it.

DMSO is also one of the most powerful painkillers known to medical science.
DMSO is a drug that produced analgesia by acting both locally and systemically. The analgesia appeared to be unrelated to that produced by morphine although the two appear to be a comparable magnitude. DMSO had a longer duration of action than morphine, 6 hr vs 2 hr, respectively. (Haigler, H.J. Comparison of the analgesic effects of dimethyl sulfoxide and morphine. Ann. N.Y. Acad. Sci. 411: 19-27 (1983). )

DMSO is used by Dr. Donsbach at his Hospital Santa Monica ( for much more than cancer, and he reports his patients respond quite well. [Donsbach, Kurt, DC, ND, PhD. Wholistic Cancer Therapy. San Diego: The Rockland Corporation, 1993] Donsbach feels that DMSO assists all the other therapies and agents he employs, and it is one therapy he administers to everyone with cancer: DMSO and hydrogen peroxide infusions. He also mentions a study at New York’s Mount Sinai Hospital where mice with leukemia were injected with DMSO and the leukemic cells began for function normally.

WARNING: Never use DMSO in an enema, never introduce it into the body rectally. If it is squirted in rectally, it will carry toxic fecal matter into the bloodstream through the intestinal wall.


DMSO for oral and topical use: They mix DMSO with pure honey, which makes it much easier on the stomach, when taken orally. Also, they ship in a glass container. The original DMSO made to Dr. Stanley W. Jacob’s exact specifications. This product is only for topical use. Do not swallow it. I have no specific information on their DMSO products. I have no specific information on their DMSO products.

Your doctor will have access to DMSO that is suitable for injections, or intravenous application, if your treament requires it.


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